Enhancing the development of and thermogenesis in brown and beige fat represents a potential treatment for obesity. In this...
Auteur - American Diabetes Association - Diabetes
Role of Glycosuria in SGLT2 Inhibitor–Induced Cardiorenal Protection:...
SGLT2 inhibitors have been shown to provide pronounced reductions in cardiorenal outcomes, including cardiovascular death...
Increased Frequency of the HLA-DRB1*04:04-DQA1*03-DQB1*03:02...
HLA-DR/DQ haplotypes largely define genetic susceptibility to type 1 diabetes (T1D). The DQB1*06:02-positive haplotype (DR15...
GIPR Agonism Enhances TZD-Induced Insulin Sensitivity in Obese IR Mice
Recent studies have found that glucose-dependent insulinotropic polypeptide receptor (GIPR) agonism can enhance the...
Roles of Activin A and Gpnmb in Metabolic Dysfunction-Associated...
Metabolic dysfunction-associated steatotic liver disease (MASLD, formerly known as nonalcoholic fatty liver disease [NAFLD])...
Genetic Analysis of Obesity-Induced Diabetic Nephropathy in BTBR Mice
Diabetic nephropathy (DN) is the leading cause of end-stage renal disease in the U.S. and has a significant impact on human...
Leptin Reduction as a Required Component for Weight Loss
Partial leptin reduction can induce significant weight loss, while weight loss contributes to partial leptin reduction. The...
Plasma Neuronal Growth Regulator 1 May Link Physical Activity to...
Habitual physical activity (PA) impacts the plasma proteome and reduces the risk of developing type 2 diabetes (T2D). Using...
Activation of METTL3 Promotes White Adipose Tissue Beiging and...
The induction of beige adipocytes in white adipose tissue (WAT), also known as WAT beiging, improves glucose and lipid...
Protective Renalase Deficiency in β-Cells Shapes Immune Metabolism...
Type 1 diabetes (T1D) is caused by the immune-mediated loss of pancreatic β-cells that produce insulin. The latest advances...