Recent advances in genetic analysis have significantly helped in progressively attenuating the heritability gap of obesity...
Auteur - American Diabetes Association - Diabetes
PTPN2 Regulates the Interferon Signaling and Endoplasmic Reticulum...
Type 1 diabetes (T1D) results from autoimmune destruction of β-cells in the pancreas. Protein tyrosine phosphatases (PTPs)...
Lactate Is a Key Mediator That Links Obesity to Insulin Resistance...
Numerous evidence indicates that inflammation in adipose tissue is the primary cause of systemic insulin resistance induced...
Pathogenic Role of Diabetes-Induced Overexpression of Kallistatin in...
It was reported previously that circulation levels of kallistatin, an endogenous Wnt signaling inhibitor, are increased in...
Hyperglycemia and Not Hyperinsulinemia Mediates Diabetes-Induced...
Type 2 diabetes (T2D) causes an increased risk of morbidity and mortality in response to viral infection. T2D is...
Methazolamide Attenuates the Development of Diabetic Cardiomyopathy...
Methazolamide (MTZ), a carbonic anhydrase inhibitor, has been shown to inhibit cardiomyocyte hypertrophy and exert a...
Differentiating Microaneurysm Pathophysiology in Diabetic Retinopathy...
Microaneurysms are biomarkers of microvascular injury in diabetic retinopathy (DR). Impaired retinal capillary perfusion is...
Genetic Predictors of Change in Waist Circumference and Waist-to-Hip...
Genome-wide association studies have identified single nucleotide polymorphisms (SNPs) associated with waist circumference...
Spatial Environment Affects HNF4A Mutation-Specific Proteome...
Studies of monogenic diabetes are particularly useful because we can gain insight into the molecular events of pancreatic β...
Glutamine Regulates Skeletal Muscle Immunometabolism in Type 2...
Dysregulation of skeletal muscle metabolism influences whole-body insulin sensitivity and glucose homeostasis. We...